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I would make an appointment with the doctor who prescribed the xyzal tablets for you. I see you joined Med help this month. Hello there, Welcome to the allergy forum. Xyzal Allergy 24HR, from Sanofi, contains levocetirizine, an antihistamine previously only available with a prescription Works while you sleep & all the next day Take Xyzal at night! Filter by condition Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content First and foremost, Allegra, Claritin, Xyzal and Zyrtec work best when taken daily rather than intermittently. However, you should be aware that potential side effects of Xyzal include sleepiness, nosebleed, fever, sore throat, dry mouth, and cough, although more severe reactions might include swelling, rash and itching. 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